In my PhD lab, we were making transgenic mice with "knock-out" genes. One of the genes we knocked out caused the mice to have spontaneous seizures when stressed. We learned how sensitive they were to this when we clapped very loudly near one, it peeled over into a seizure..
Later, we learned that certain cells in their hippocampus committed suicide when this happened, where in normal mice these cells were protected. Of course, these animals are potential models for ischemial stroke research. :)
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timeasmymeasure
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Date: 2007-07-04 09:06 pm (UTC)In my PhD lab, we were making transgenic mice with "knock-out" genes. One of the genes we knocked out caused the mice to have spontaneous seizures when stressed. We learned how sensitive they were to this when we clapped very loudly near one, it peeled over into a seizure..
Later, we learned that certain cells in their hippocampus committed suicide when this happened, where in normal mice these cells were protected. Of course, these animals are potential models for ischemial stroke research. :)